We aimed to optimize the biocompatibility of ClariVy™ Cervical IBF System implants. The ClariVy™ Cervical IBF System consists of spinal implants made from polyether-ketone-ketone polymer (PEKK). Though this polymer shows much potential due to its high biocompatibility, it remains biologically inert, which prevents it from reacting to tissue cells and ultimately rejects cell adhesion. PEKK emerged as the newest polymer implant material, following the similar polymer PEEK (poly-ether-ether-ketone). This polymer contained similar properties to PEKK, such as high biocompatibility.

Patient anxiety leads many to avoid healthcare and drill vibrations significantly contribute to patient discomfort in dental situations. These vibrations are transmitted through bone structure, causing physical discomfort and amplifying stress during procedures. We developed WhisperGuard to reduce patient anxiety by absorbing vibrations from dental drills. The device utilizes materials with high damping coefficients and vibration-damping properties, such as Sorbothane, polyurethane and EDM1029.

We designed the Catheter Deflection Verification System (CDVS) as a quality assurance tool to enhance the precision and reliability of catheters used in cardiac ablation procedures. Accurate energy delivery to specific heart regions is essential for successful ablation, as variability in catheter deflections can lead to incomplete lesion formation, unintended tissue damage or additional procedures. The CDVS ensures a 1:1 translation between input angles applied at the catheter handle and output angles observed at the tip.

Gout affects about 1 out of every 25 Americans, but patients cannot monitor their blood uric acid levels and anticipate flare-ups. Even for patients who closely manage their diet, flare-ups still occur and can be debilitating. We developed a continuous uric acid monitor to inform patients of their blood uric acid levels and help manage their gout symptoms before a flare-up occurs. Using microelectrodes and an enzymatic reaction, our device quantifies and monitors the concentration of uric acid in the blood.

People with congenital differences in their hands and limbs often adapted as children to lead wonderful and productive lives. However, as they age, dexterity decreases and these patients need assistance to perform everyday tasks such as holding a telephone or opening a car door. A local man encountered this issue and contacted the College of Engineering for a solution to help him remain active. We developed a customized assistive device that fit precisely to his hand and increased his ability to grip and hold objects.

We designed the Mayo BIBS EMG Device as a novel, noninvasive electromyographic (EMG) monitoring system to help healthcare professionals assess extubation readiness in intensive care unit (ICU) patients. By capturing and analyzing real-time EMG signals from interclavicular muscles, our portable device provides objective, quantitative data on respiratory muscle activity and strength, enhancing clinical decision-making for extubation.

Hydrocephalus is a condition where the cerebrospinal fluid (CSF) buildup in the cranium increases pressure on the brain. Current shunts drain CSF from the brain to other body parts where it can be reabsorbed; however, existing shunts fail after about two years. We developed a lumbar shunt that drained CSF from the lumbar spine to the venous system. A key feature of our design includes a ball-and-spring valve mechanism, which ensures precise flow regulation and prevents backflow, addressing a primary challenge of existing shunt systems.

Firefighters operate in high-stress environments that expose them to extreme physical exertion and hazardous conditions, necessitating robust health monitoring solutions. We developed a wearable respiration rate sensor designed to band around the chest, providing real-time monitoring tailored to firefighters’ unique needs. This compact and durable sensor tracks respiratory patterns with high accuracy, leveraging advanced algorithms to ensure reliable data collection even under dynamic conditions.

We created a knee exoskeleton for people recovering from total knee replacement surgery. Our device provided mechanical resistance, electrical therapy and data collection as a cost-effective, at-home solution for knee recovery. With this device, patients complete guided therapy exercises, helping them build stronger quadriceps muscles and improve mobility.

We developed Head Armor Pro to address concussions and traumatic brain injuries (TBIs) in youth football, where current helmet designs inadequately protect against combined linear and rotational forces. We created an innovative helmet accessory that integrates auxetic foam padding and real-time impact monitoring sensors to significantly enhance player safety. Auxetic foam, with its unique energy-dissipation properties, reduces linear and rotational forces, addressing critical gaps in existing helmet technologies.